Mark Robins has made one change to the side that beat Stoke City in the third round of the FA Cup as Lee Burge returns.
Liam O'Brien, who was only beaten from the spot by the Premier League side, returns to the bench.
Rod McDonald also returns the bench after some time out injured with a groin strain.
Elsewhere, the Sky Blues line up as normal with Jack Grimmer, Tom Davies, Jordan Willis and Chris Stokes at the back.
In central midfield Tom Bayliss keeps his places as Liam Kelly continues to fight back from a heel injury, alongside Michael Doyle.
Jordan Maguire-Drew makes his league debut for City as Jordan Shipley completes the midfield.
Marc McNulty annd Max Biamou line-up together in attack.
Coventry City XI: Burge (GK), Grimmer, Davies, Willis, Stokes; Maguire-Drew, Bayliss, Doyle (C), Shipley; Biamou, McNulty.
Subs: O'Brien (GK), McDonald, Beavon, Haynes, Barrett, Stevenson, Ponticelli.
Exeter City XI: Pym (GK), Sweeney, James, Archibald-Henville, Tillson, Harley, Holmes, Stockley, Seaborne, Moxey, Taylor (C).
Subs: Jones (GK), Woodman, Simpson, McAlinden, Jay, Wilson, Boateng.