Coventry City Manager Mark Robins has made two changes to the team which lost to Accrington Stanley on Saturday.
Ryan Haynes replaces Chris Stokes to make his first league start this season after recovering from a medial collateral ligament injury.
Meanwhile Stuart Beavon starts in place of Max Biamou to accompany Duckens Nazon, Jodi Jones and Marc McNulty in attack for Robins' side.
Liam Kelly, who returned from injury last time out, keep his place alongside Michael Doyle in the centre of the park, with Lee Burge, Jordan Willis, Rod McDonald and Jack Grimmer also in the starting eleven with Grimmer making his eighteenth consecutive start.
Coventry City XI: Burge (GK); Grimmer, Willis, McDonald, Haynes, Kelly, Doyle (C), Jones, Nazon, McNulty, Beavon.
Subs: O'Brien (GK), Davies Shipley, Vincenti, Stevenson, Biamou, Ponticelli.
Colchester United XI: Walker (GK), Jackson, Lapslie, Kent, Wright, Comley, Murray, Eastman, Mandron, Hanlan, Inniss.
Subs: Gilmartin (GK), Kinsella, Kabamba, O'Sullivan, Slater, Odelusi, James,
Referee: Mr M. Sailsbury.