Reice Charles-Cook continues in goal after heroics in the last round...
Russell Slade makes four changes to the side that started at the weekend, with a new look back four as Nathan Clarke and Farrend Rawson are ineligible for the competition.
Reice Charles-Cook will start in goal, having saved two penalties in the shootout at Swansea, while Dion Kelly-Evans, Jordan Turnbull and Cian Harries come in to the back four.
Callum Reilly and Andy Rose continue as the central midfield pairing, flanked by George Thomas and Kyel Reid.
Marcus Tudgay will play off Stuart Beavon in attack.
Coventry City: Charles-Cook (GK), Di.Kelly-Evans, Turnbull, Harries, Haynes, Reilly, Rose, G.Thomas, Reid, Beavon, Tudgay (C).
Subs: Burge (GK), Finch, Bigirimana, Stevenson, Gadzhev, Lameiras, Jones.
Wycombe Wanderers: Blackman (GK), Jombati, Jacobson (C), Stewart, Thompson, Bean, Harriman, O'Nien, Weston, de Havilland, Saunders.
Subs: Richardson (GK), Wood, Akinfenwa, Muller, Freeman, Kashket.