Dan Agyei returns to lead the line, while Andre Wright is recalled to the starting XI...
Mark Venus makes four changes from the side that advanced in the Checkatrade Trophy, with Lee Burge and Dion Kelly-Evans among those returning to the starting XI.
Burge replaces Reice Charles-Cook in net, while Kelly-Evans slots alongside a back four of Jordan Turnbull, Jordan Willis and Lewis Page. Gael Bigirimana, Andy Rose and Chris McCann form a midfield trio as Agyei and Wright return to partner Marvin Sordell in attack.
George Thomas and Jodi Jones are available from the bench.
Coventry City: Burge (GK), Di. Kelly-Evans, Willis (C), Turnbull, Page, Rose, McCann, Bigirimana, Sordell, Wright, Agyei.
Subs: Charles-Cook (GK), Maycock, Gadzhev, Jones, Reid, G.Thomas, Tudgay.
Southend United: Oxley (GK), Demetriou, Thompson, Ferdinand (C), Timlin, O'Neill, Wordsworth, Leonard, McLaughlin, Cox, Ranger.
Subs: Smith (GK), White, King, Bridge, Fortune, McGlashan, Sokolik.