The Sky Blues head to Luton's Kenilworth Road to face the free-scoring Hatters in SkyBet League Two.
Luton are the highest scorers in England having found the net 34 times already this season in just 15 games.
A win for the Sky Blues, who still carry the best defensive record in the Football League, and they could climb as high as fifth in the standings despite recent poor results.
The Hatters are without any real injury concerns and are likely to name an unchanged eleven despite a goalless draw with Crawley Town.
Manager Nathan Jones is enjoying early success in his first permenant managment role in Football. Jones was caretaker manager at Brighton in 2014 and Saturday will mark his 100th game with Luton, wining an impressive half of those.
Jordan Willis and Rod McDonald will have done their research on Danny Hylton and James Collins. The duo are battling at the top of Luton's scoring charts having notched eight goals each. Hylton managed 21 league goals last season after moving from Oxford United in 2016 and has certainly been Luton's main focal point in attack.
Luton's one-to-watch on Saturday is midfielder Luke Berry. The 25-year-old moved to Kenilworth Road from childhood club and rivals Cambridge United in the summer where he scored 53 goals from the middle of the park.
Alongside Berry in midfield is former Walsall and Charlton midfielder, Jordan Cook. The Sunderland Academy graduate, who can play central and out-wide, was offered a new contract with the Saddlers but opted to move to Luton where he has been a regular in the starting eleven.
In defence for the Hatters is club captain and fomrer Scotland U21 interntional Scott Cuthbert. The 6ft2 central defender who started his career with Celtic has made over 200 Football League appearances, with the majority coming for Leyton Orient in League One.
First half goals from Stern John and Gary McSheffrey were enough to give the Sky Blues all three points when they beat Luton 2-1 at Kenilworth Road in 2006.
An Adrian Williams own goal with five minutes to go did give the Hatters some hope but City managed to hang on to take the away win.
Current City captain Michael Doyle played all 90 minutes in midfield alongside Stephen Hughes and Don Hutchison.
Coventry finished eighth that season in the Coca-Cola Championship during their first season at the Ricoh Arena, the highest finish since relegation from the top flight.
Last Six Meetings
W Coventry City 1-0 Luton Town - 30th Jan 2007 - Championship
L Luton Town 3-1 Coventry City - 23rd Dec 2006 - Championship
W Luton Town 1-2 Coventry City - 15th Apr 2006 - Championship
W Coventry City 1-0 Luton Town - 29th Oct 2005 - Championship
L Luton Town 2-0 Coventry City - 27th Oct 1998 - League Cup
L Luton Town 1-0 Coventry City - 20th Dec 1991 - Division One